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1

Induction of suppressors of cytokine signaling (SOCS) in the retina during experimental autoimmune uveitis (EAU): Potential neuroprotective role of SOCS proteins

H. Takase, C.-R. Yu, X. Liu, C. Fujimoto, I. Gery, C.E. Egwuagu

Journal:

Journal of Neuroimmunology

Year:

2005

Language:

english

File:

PDF, 346 KB

english, 2005

2

Synthesis and analysis of the enantiomers of calmidazolium, and a 1H NMR demonstration of a chiral interaction with calmodulin

Andrew J. Edwards, Patricia J. Sweeney, David G. Reid, John M. Walker, Nabil Elshourbagy, Charles E. Egwuagu, James F. Young, Curtis L. Patton

Journal:

Year:

1996

Language:

english

File:

PDF, 454 KB

english, 1996

3

Persistence of IL-2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis

Cheng-Rong Yu, Hyun-Mee Oh, Nady Golestaneh, Ahjoku Amadi-Obi, Yun S. Lee, Amarachi Eseonu, Rashid M. Mahdi, Charles E. Egwuagu

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 567 KB

english, 2011

4

Erratum to “Immunotolerance toward native αA-crystallin in knockout mice deficient in the functional protein”: [Immunology Letters 89/2–3 (2003) 259–265]

Puwat Charukamnoetkanok, James P. Brady, Eric F. Wawrousek, Charles E. Egwuagu, J.Samuel Zigler Jr, Barbara P. Vistica, Scott M. Whitcup, Igal Gery

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 34 KB

english, 2003

5

Immunotolerance toward native αA-crystallin in knockout mice deficient in the functional protein

Puwat Charukamnoetkanok, James P. Brady, Eric F. Wawrousek, Charles E. Egwuagu, J.Samuel Zigler Jr, Barbara P. Vistica, Scott M. Whitcup, Igal Gery

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 306 KB

english, 2003

6

Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10

Yun Sang Lee, Ahjoku Amadi-Obi, Cheng-Rong Yu, Charles E. Egwuagu

Journal:

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

7

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

Amadi-Obi, Ahjoku, Yu, Cheng-Rong, Liu, Xuebin, Mahdi, Rashid M, Clarke, Grace Levy, Nussenblatt, Robert B, Gery, Igal, Lee, Yun Sang, Egwuagu, Charles E

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 451 KB

english, 2007

8

Interferon-γ induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors

Egwuagu, C E, Li, W, Yu, C-R, Che Mei Lin, M, Chan, C-C, Nakamura, T, Chepelinsky, A B

Journal:

Year:

2006

Language:

english

File:

PDF, 444 KB

english, 2006

9

Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals

Evans, M K, Yu, C-R, Lohani, A, Mahdi, R M, Liu, X, Trzeciak, A R, Egwuagu, C E

Journal:

Year:

2006

Language:

english

File:

PDF, 316 KB

english, 2006

10

Skewed Abrogation of Tolerance to a Neo Self-Antigen in Double-Transgenic Mice Coexpressing the Antigen with Interleukin-1β or Interferon-γ

Meifen Zhang, Atsuki Fukushima, Barbara P. Vistica, Stephen J. Kim, Lang Hung, Eric F. Wawrousek, Charles E. Egwuagu, Robert S. Lee, Scott M. Whitcup, Igal Gery

Journal:

Cellular Immunology

Year:

2001

Language:

english

File:

PDF, 101 KB

english, 2001

11

Bacterial optic disk mass and toxoplasmic-like encephalitis in an HIV-seropositive subject

Ahmad M. Mansour, Naseem H. Ansari, Charles E. Egwuagu, Hanna G. Kaspar, M. Kevin Harmon

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

1993

Language:

english

File:

PDF, 2.96 MB

english, 1993

12

Expression of Interferon-γ in the Lens Exacerbates Anterior Uveitis and Induces Retinal Degenerative Changes in Transgenic Lewis Rats

Charles E. Egwuagu, Rashid M. Mahdi, Chi-Chao Chan, Jorge Sztein, Wenmei Li, Janine A. Smith, Ana B. Chepelinsky

Journal:

Clinical Immunology

Year:

1999

Language:

english

File:

PDF, 380 KB

english, 1999

13

γInterferon Expression Disrupts Lens and Retinal Differentiation in Transgenic Mice

Charles E. Egwuagu, Jorge Sztein, Chi-Chao Chan, Rashid Mahdi, Robert B. Nussenblatt, Ana B. Chepelinsky

Journal:

Developmental Biology

Year:

1994

File:

PDF, 1.23 MB

1994

14

Interferon Regulatory Transcription Factors Are Constitutively Expressed and Spatially Regulated in the Mouse Lens

Wenmei Li, Chandrasekharam N. Nagineni, Bassey Efiok, Ana B. Chepelinsky, Charles E. Egwuagu

Journal:

Developmental Biology

Year:

1999

Language:

english

File:

PDF, 1.27 MB

english, 1999

15

Extralenticular Expression of the αA-Crystallin Promoter/Gamma Interferon Transgene

CHARLES E. EGWUAGU, ANA B. CHEPELINSKY

Journal:

Experimental Eye Research

Year:

1997

Language:

english

File:

PDF, 402 KB

english, 1997

16

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases

Charles E. Egwuagu

Journal:

Year:

2009

Language:

english

File:

PDF, 562 KB

english, 2009

17

The level of thymic expression of RPE65 inversely correlates with its capacity to induce experimental autoimmune uveitis (EAU) in different rodent strains

Don-Il Ham, Chiaki Fujimoto, Susan Gentleman, Chi-Chao Chan, Cheng-Rong Yu, Shirley Yu, Charles E. Egwuagu, T. Michael Redmond, Igal Gery

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

18

SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy

Charles E. Egwuagu, Cheng-Rong Yu, Zhuqing Li, Robert B. Nussenblatt

Journal:

Journal of Autoimmunity

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

19

Immunoproteasome expression in a nonimmune tissue, the ocular lens

Shaneen Singh, Niranjan Awasthi, Charles E Egwuagu, B.J Wagner

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 296 KB

english, 2002

20

Predominant usage of Vβ8.3 T cell receptor in a T cell line that induces experimental autoimmune uveoretinitis (EAU)

Charles E. Egwuagu, Sina Bahmanyar, Rashid M. Mahdi, Robert B. Nussenblatt, Igal Gery, Rachel R. Caspi

Journal:

Clinical Immunology and Immunopathology

Year:

1992

Language:

english

File:

PDF, 1.21 MB

english, 1992

21

STAT3 Activates miR-155 in Th17 Cells and Acts in Concert to Promote Experimental Autoimmune Uveitis

Escobar, Thelma, Yu, Cheng-Rong, Muljo, Stefan A., Egwuagu, Charles E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 886 KB

english, 2013

22

Suppressor of Cytokine Signaling 3 Regulates Proliferation and Activation of T-helper Cells

Yu, C.-R., Mahdi, R. M., Ebong, S., Vistica, B. P., Gery, I., Egwuagu, C. E.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 839 KB

english, 2003

23

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

Wang, Ren-Xi, Yu, Cheng-Rong, Dambuza, Ivy M, Mahdi, Rashid M, Dolinska, Monika B, Sergeev, Yuri V, Wingfield, Paul T, Kim, Sung-Hye, Egwuagu, Charles E

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 5.42 MB

english, 2014

24

SOCS3 Deletion in T Lymphocytes Suppresses Development of Chronic Ocular Inflammation via Upregulation of CTLA-4 and Expansion of Regulatory T Cells

Yu, C.-R., Kim, S.-H., Mahdi, R. M., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

25

African trypanosomes contain calmodulin which is distinct from host calmodulin

RUBEN, L, EGWUAGU, C, PATTON, C

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1983

Language:

english

File:

PDF, 970 KB

english, 1983

26

Expression of excision repair genes in non-malignant bone marrow from cancer patients

Dabholkar, Meenakshi, Bostick-Bruton, Frieda, Weber, Christine, Egwuagu, Charles, Bohr, Vilhelm A., Reed, Eddie

Journal:

Mutation Research/DNA Repair

Year:

1993

Language:

english

File:

PDF, 930 KB

english, 1993

27

T cell receptor β-chain usage in experimental autoimmune uveoretinitis

Egwuagu, Charles E., Chow, Christopher, Beraud, Evelyne, Caspi, Rachel R., Mahdi, Rashid M., Brézin, Antoine P., Nussenblatt, Robert B., Gery, Igal

Journal:

Journal of Autoimmunity

Year:

1991

Language:

english

File:

PDF, 1.64 MB

english, 1991

28

Identification of Toxoplasma gondii in Paraffin-Embedded Sections by the Polymerase Chain Reaction

Brézin, Antoine P., Egwuagu, Charles E., Burnier, Miguel, Silveira, Claudio, Mahdi, Rashid M., Gazzinelli, Ricardo T., Belfort, Rubens, Nussenblatt, Robert B.

Journal:

American Journal of Ophthalmology

Year:

1990

Language:

english

File:

PDF, 1.13 MB

english, 1990

29

Usage of TCR Vγ2 + T Lymphocytes in Experimental Autoimmune Uveoretinitis

Egwuagu, Charles E., Smith, Janine A., Kozhich, Alexander T., Mahdi, Rashid M.

Journal:

Ocular Immunology & Inflammation

Year:

1996

Language:

english

File:

PDF, 1020 KB

english, 1996

30

Expression of ocular autoantigens in the mouse thymus

Charukamnoetkanok, Puwat, Fukushima, Atsuki, Whitcup, Scott M., Gery, Igal, Egwuagu, Charles E.

Journal:

Current Eye Research

Year:

1998

File:

PDF, 1.10 MB

1998

31

CENTRAL TOLERANCE MECHANISMS IN CONTROL OF SUSCEPTIBILITY TO AUTOIMMUNE UVEITIC DISEASE

GERY, IGAL, EGWUAGU, CHARLES E.

Journal:

International Reviews Of Immunology

Year:

2002

Language:

english

File:

PDF, 924 KB

english, 2002

32

Immunopathology of ocular onchocerciasis 3. Th-2 helper T cells in the conjunctiva

Chan, Chi-Chao, Li, Qian, Brezin, Antoine P., Whitcup, Scott M., Egwuagu, Charles, Otteson, Eric A., Nussenblatt, Robert B.

Journal:

Ocular Immunology & Inflammation

Year:

1993

Language:

english

File:

PDF, 1.23 MB

english, 1993

33

Therapeutic targeting of STAT pathways in CNS autoimmune diseases

Egwuagu, Charles E., Larkin, III, Joseph

Journal:

Year:

2013

Language:

english

File:

PDF, 713 KB

english, 2013

34

Constitutive and Cytokine-Induced GITR Ligand Expression on Human Retinal Pigment Epithelium and Photoreceptors

Kim, Ben J., Li, Zhuqing, Fariss, Robert N., Shen, De Fen, Mahesh, Sankaranarayana P., Egwuagu, Charles, Yu, Cheng-Rong, Nagineni, Chandrasekharam N., Chan, Chi-Chao, Nussenblatt, Robert B.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2004

Language:

english

File:

PDF, 476 KB

english, 2004

35

SOCS1 Regulates CCR7 Expression and Migration of CD4+ T Cells into Peripheral Tissues

Yu, C.-R., Mahdi, R. M., Liu, X., Zhang, A., Naka, T., Kishimoto, T., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

36

Suppressors of Cytokine Signaling Proteins Are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance

Egwuagu, C. E., Yu, C.-R., Zhang, M., Mahdi, R. M., Kim, S. J., Gery, I.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 436 KB

english, 2002

37

Dendritic Cell Maturation Requires STAT1 and Is under Feedback Regulation by Suppressors of Cytokine Signaling

Jackson, S. H., Yu, C.-R., Mahdi, R. M., Ebong, S., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 538 KB

english, 2004

38

Cell Proliferation and STAT6 Pathways Are Negatively Regulated in T Cells by STAT1 and Suppressors of Cytokine Signaling

Yu, C.-R., Mahdi, R. M., Ebong, S., Vistica, B. P., Chen, J., Guo, Y., Gery, I., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 596 KB

english, 2004

39

STAT3 Protein Interacts with Class O Forkhead Transcription Factors in the Cytoplasm and Regulates Nuclear/Cytoplasmic Localization of FoxO1 and FoxO3a Proteins in CD4+ T Cells

Oh, H.-M., Yu, C.-R., Dambuza, I., Marrero, B., Egwuagu, C. E.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

40

Pertussis Toxin Is Superior to TLR Ligands in Enhancing Pathogenic Autoimmunity, Targeted at a Neo-Self Antigen, by Triggering Robust Expansion of Th1 Cells and Their Cytokine Production

Fujimoto, C., Yu, C.-R., Shi, G., Vistica, B. P., Wawrousek, E. F., Klinman, D. M., Chan, C.-C., Egwuagu, C. E., Gery, I.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 830 KB

english, 2006

41

Key role for IL-21 in experimental autoimmune uveitis

Wang, L., Yu, C.-R., Kim, H.-P., Liao, W., Telford, W. G., Egwuagu, C. E., Leonard, W. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

42

STAT3 Protein Promotes T-cell Survival and Inhibits Interleukin-2 Production through Up-regulation of Class O Forkhead Transcription Factors

Oh, H.-M., Yu, C.-R., Golestaneh, N., Amadi-Obi, A., Lee, Y. S., Eseonu, A., Mahdi, R. M., Egwuagu, C. E.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.52 MB

english, 2011

43

Suppressors of Cytokine-Signaling Proteins Induce Insulin Resistance in the Retina and Promote Survival of Retinal Cells

Liu, X., Mameza, M. G., Lee, Y. S., Eseonu, C. I., Yu, C.-R., Kang Derwent, J. J., Egwuagu, C. E.

Journal:

Year:

2008

Language:

english

File:

PDF, 384 KB

english, 2008

44

Interleukin 12 (IL-12) family cytokines: Role in immune pathogenesis and treatment of CNS autoimmune disease

Sun, Lin, He, Chang, Nair, Lekha, Yeung, Justine, Egwuagu, Charles E.

Journal:

Year:

2015

Language:

english

File:

PDF, 789 KB

english, 2015

45

Autoreactive Memory CD4+ T Lymphocytes That Mediate Chronic Uveitis Reside in the Bone Marrow through STAT3-Dependent Mechanisms

Oh, H.-M., Yu, C.-R., Lee, Y., Chan, C.-C., Maminishkis, A., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.78 MB

english, 2011

46

Interferon Consensus Sequence-binding Protein Is Constitutively Expressed and Differentially Regulated in the Ocular Lens

Li, W., Nagineni, C. N., Ge, H., Efiok, B., Chepelinsky, A. B., Egwuagu, C. E.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 1.03 MB

english, 1999

47

Suppressor of Cytokine Signaling 1 (SOCS1) Mitigates Anterior Uveitis and Confers Protection Against Ocular HSV-1 Infection

Yu, Cheng-Rong, Hayashi, Kozaburo, Lee, Yun Sang, Mahdi, Rashid M., Shen, De Fen, Chan, Chi-Chao, Egwuagu, Charles E.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.75 MB

english, 2015

48

ERCC1 and ERCC2 Expression in Malignant Tissues From Ovarian Cancer Patients

Dabholkar, M., Bostick-Bruton, F., Weber, C., Bohr, V. A., Egwuagu, C., Reed, E.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1992

Language:

english

File:

PDF, 5.43 MB

english, 1992

49

Loss of STAT3 in CD4+ T Cells Prevents Development of Experimental Autoimmune Diseases

Liu, X., Lee, Y. S., Yu, C.-R., Egwuagu, C. E.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 473 KB

english, 2008

50

Novel IL27p28/IL12p40 Cytokine Suppressed Experimental Autoimmune Uveitis by Inhibiting Autoreactive Th1/Th17 Cells and Promoting Expansion of Regulatory T Cells

Wang, R.-X., Yu, C.-R., Mahdi, R. M., Egwuagu, C. E.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.73 MB

english, 2012

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